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br Conflicts of interest br Acknowledgments Work in
2021-01-04
Conflicts of interest Acknowledgments Work in the laboratory of SPS is funded by Council of Scientific and Industrial Research (CSIR) Network Project BSC-0111 (INDEPTH) and BSC-0112 (NanoSHE). We are thankful to Director, CSIR-IITR for his constant encouragement and support. We also acknowledg
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br Disclosures br Introduction The presence
2021-01-04
Disclosures Introduction The presence of anti-viral T-cell immunity is crucial for effective and sustained protection against Cytomegalovirus (CMV) following allogeneic stem cell transplantation (alloSCT) [1]. In vitro and in vivo T-cell depletion (TCD) via addition of the anti-CD52 monoclonal
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Role of ROS signaling in regulating
2021-01-04
Role of ROS signaling in regulating cell death pathways has been well established. Involvement of CLIC1 in ROS production has been studied earlier. It was observed that macrophages from clic1 mice showed ~30% decrease in cellular ROS generation which effects macrophage function (Jiang et al., 2012).
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Rice approximately covers of land area of the earth
2021-01-04
Rice approximately covers 1% of land area of the earth and it is one of the main sources of food for billions of people [4]. One of the main agriculture industry residues is rice husk, which contains high amount of amorphous silica up to 85–95%. Rice husk ash (RHA) is a solid residue of rice husk co
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Acknowledgments br Introduction Steroidogenesis the process
2021-01-04
Acknowledgments Introduction Steroidogenesis, the process of testosterone synthesis, occurs in the adrenal cortex, testis and ovary, and it is controlled by luteinizing hormone (LH), which is synthesized and secreted from the pituitary (Hanukoglu, 1992, Payne and Youngblood, 1995). In the testis
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br Methods br Results br Discussion There are two particular
2021-01-04
Methods Results Discussion There are two particularly important facets of the present ERK findings relevant to drug conditioning. One is the strong ERK signal observed in the medial prefrontal cortex and the nucleus accumbens during the immediate post-trial interval following the final cond
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In SLO permeabilized human sperm the AR elicited by calcium
2021-01-04
In SLO-permeabilized human sperm, the AR elicited by calcium, persistently active Arf6 [41] and Rab3A, 8-pCPT-2′-O-Me-cAMP [8], diacylglycerol and a non-hydrolyzable analog [35], is sensitive to the PLC blocker U73122. Furthermore, 8-pCPT-2′-O-Me-cAMP elicits a calcium signal in non-permeabilized sp
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Only a few studies have examined the effect of prostanoids
2021-01-04
Only a few studies have examined the effect of prostanoids on cardiac fibroblasts. Therefore, this study examines the effect of PGE2 on cardiac fibroblast proliferation and tests the hypothesis that PGE2 causes cardiac fibroblast proliferation via alterations of Ezetimibe regulatory molecules and th
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623 mg In principle in vitro techniques for assessing enzyme
2021-01-04
In principle, in vitro techniques for assessing enzyme induction might include the use of cultured hepatocytes, precision-cut liver slices, immortalized 623 mg lines (such as those derived from hepatomas) and reporter gene constructs (where appropriate cells are transfected with recombinant DNA enc
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In this report we present spectroscopic evidence on the effe
2020-12-31
In this report, we present spectroscopic evidence on the effect of different solvents having proton acceptor and proton donor ability and pH of the medium on the abstraction of amino proton of PI (Scheme 1) for controlling the nonradiative rates. Despite the general utility of PI as a DNA intercalat
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br Results br Discussion Unraveling the molecular details of
2020-12-31
Results Discussion Unraveling the molecular details of nucleoporin-karyopherin interactions, which have to be strong enough to promote transport but sufficiently weak to avoid stalling of transport complexes within the pore, is key to our understanding of the mechanisms of nucleocytoplasmic tr
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Preparation of the pyridyl ether
2020-12-31
Preparation of the 2-pyridyl ether analogs (–) was accomplished by alkylation of alcohol with 2-bromopyridines in the presence of NaH to afford the desired pyridyl ether analogs in low to moderate yield. Preparation of the 3-pyridyl analog was carried out by conversion of alcohol to the tosylate,
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Sterol regulatory element binding proteins SREBPs
2020-12-31
Sterol regulatory element binding proteins (SREBPs) regulate transcription of genes involved in fatty bgj receptor synthesis [38] (fatty acid synthase, and acetyl-CoA carboxylase) as well as triglyceride synthesis [39]. SREBP-1 protein levels are reduced in 3T3-F442A adipocytes [40] and increased i
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A topological property P is said to be
2020-12-31
A topological property P is said to be cut point hereditary [3] if whenever a space X has property P, then, for every there exists some separation of such that each of and has property P. A space X is called connected ordered topological space (COTS) [5] if it is connected and has the property: if
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CK enzymes belong to a
2020-12-31
CK1 enzymes belong to a conserved family of serine/threonine protein kinases that plays an important and diverse role in vesicular trafficking, DNA repair, hiv protease inhibitor progression and cytokinesis in organisms from yeast to humans [15]. In multicellular organisms CK1 enzymes also regulate
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