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atr inhibitor br Other drugs Overdose of
2019-04-20

Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium atr inhibitor and thus to unmask a BrS phenotype [60].
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Although the CHADS score is
2019-04-20

Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so
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pdgf receptor El recorrido inicia con una
2019-04-20

El recorrido inicia con una revisión de las colaboraciones de Paz en la revista entre la que destaca la del número 197, de marzo de 1951. El famoso de David Rousset en torno pdgf receptor los campos de concentración en la . Lo que marcaría la ruptura de Paz con la izquierda stalinista latinoameric
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The conventional cutoff for small for gestational age is bas
2019-04-20

The conventional cutoff for small for gestational age is based on birthweight, which is suitable for infants born at term but is far less appropriate for those born preterm. Preterm birth is itself pathological, and ultrasound-based estimates of fetal weight show that infants born preterm are much s
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In addition we are continuing our regular editorial
2019-04-20

In addition, we are continuing our regular editorial policies of commissioning more specialised Clinical Reviews and Series across Group to provide a more focused and in-depth assessment for key diseases. And beyond providing knowledge and information, we want to encourage academic and practising c
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En este sentido la idea de crisis alude ante todo
2019-04-20

En este sentido, la idea de crisis alude ante todo, GDC-0941 una noción de cambio, que puede ser abrupto y radical —como en la noción de cambio revolucionario, o en la teoría de la crisis del capitalismo como colapso; o puede referirse más bien a una modificación o trastocamiento paulatino, crónico
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We report a case of
2019-04-19

We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con
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br Conclusion br Introduction Multiple
2019-04-19

Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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br Discussion In this pilot
2019-04-19

Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre
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It is good to see
2019-04-19

It is good to see any cluster-randomised abacavir trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and colleagues is rare in the
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br Drug resistant tuberculosis threatens to
2019-04-19

Drug-resistant tuberculosis threatens to undermine advances in tuberculosis control worldwide. Multidrug-resistant tuberculosis (MDRTB), defined as resistance to isoniazid and rifampicin, requires treatment for up to 24 months with expensive diagnostics and second-line drugs. Fewer than 15% of pat
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Estos cuatro momentos expresan los pasos m
2019-04-19

Estos cuatro momentos expresan los pasos más importantes del desprendimiento de la crítica y la práctica literaria en relación con la política partidista. Es decir, son tomas de posición estético-literarias que abrigan en su interior tomas de posición política que, amc 7 la postre, socavan los cimie
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Independientemente del estado de nimo de
2019-04-19

Independientemente del estado de ánimo de los agentes del gobierno colonial, ante el fin de la ocupación militar, La Lucha presentaba el advenimiento de la República de Cuba como un hecho con claroscuros para diferentes sectores de la sociedad cubana; por un lado, se anhelaba la salida del gobierno
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No se trata de una simple par
2019-04-19

No se trata de una simple paráfrasis de “ellos saben muy bien lo que hacen, pero aun así lo hacen”, porque al interpretar el sentido que asume el entramado social, relacional, como depositario de las “acciones” reformistas estatales, es evidente que existe una necesidad por estructurar la propia rea
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In patients with typical atrial flutter circulating around
2019-04-18

In patients with typical atrial flutter circulating around the tricuspid valve, the verification of a bidirectional conduction block is recommended for cavotricuspid isthmus (CTI) ablation, because a unidirectional conduction block at the CTI has been previously reported to cause recurrence of atria
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