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Paying now rather than forever has never been
2019-04-15

Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set
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Entre los cronistas y sin dejar atr s esta
2019-04-15

Entre los cronistas, y sin dejar atrás esta concepción de la naturaleza y sin que se perciba un mayor conflicto, se advierte, en mayor o menor medida, un acentuado interés por los seres naturales y las “causas segundas”. La razón de esta falta de conflicto frontal obedece, por un lado, al reconocimi
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Esta autonom a junto a su
2019-04-15

Esta autonomía, junto cediranib su propósito de cambio social y su propuesta de una novedosa perspectiva sobre la política, convierte a los movimientos sociales en una particular fuente de conflicto, incluso en el contexto de estos países estudiados. La conflictividad es uno de los ejes presentes en
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br Authorship br Conflict of
2019-04-15

Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal order Batimastat mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) an
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Another recent study also concluded that presence of EMD at
2019-04-15

Another recent study also concluded that presence of EMD at diagnosis, rather than any treatment modalities ever used, was the only significant predictor of extramedullary recurrence. This finding suggests that the development of EMD, even during treatment, may possibly reflect different tumor biolo
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There are several shortcomings to this study that
2019-04-11

There are several shortcomings to this study that need to be considered. The small size of this series is an obvious shortcoming. Due to the relative rarity of the disease, this problem is not unique to this series and authors of a recent meta-analysis noted the small sample size of other studies as
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Long run elasticity ln Long run semi elasticity The function
2018-11-15

Long-run elasticity: lnπ=1.06; Long-run semi-elasticity: π=0.29. The functional form given by (9) is not rejected, so that the money inelasticity notch inhibitor is rejected. Note also that the hypothesis of an elasticity equal to one (a1=1, Eq. (13)) could not be rejected. The value of the coeffic
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Currently there are no medications or modalities
2018-11-15

Currently, there are no medications or modalities to reduce both visceral adiposity as well as chronic inflammation in MS or T2DM subjects. Recently, we (Morino et al., 2008a; Adachi et al., 2010) and others (Chung et al., 2008; Gupte et al., 2009) have shown that the beneficial metabolic advantages
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Our voxel based morphometry analysis of the S
2018-11-15

Our voxel based morphometry analysis of the S-NR group provided a more specific cluster of reduced volume within the left middle frontal gyrus — which improved the specificity of this step of the decision tree from 77% to 89%. At a whole guanylyl cyclase level no other GM regions were associated wi
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Furthermore the inhibitor binding can
2018-11-15

Furthermore, the inhibitor binding can also be altered by various mutations. Prime examples are acquired intrinsic resistance mutations that have marred the success of tyrosine kinase inhibitors (TKIs) such as gefitinib, erlotinib and imanitib, prompting efforts for second- and third-line treatments
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br Acknowledgments The data was collected with funding from
2018-11-15

Acknowledgments The data was collected with funding from the East Carolina University Department of Economics. Ju-Chin Huang collaborated with the author on the survey design. Value of the data Materials and methods Specifications table Data, experimental design, materials and methods
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br Conclusions br Acknowledgements This research was
2018-11-15

Conclusions Acknowledgements This research was supported by Grant no. BMBF 01EV0711 (German Ministry of Education and Research) and by the IMAGEN Project (PL037286) of the European Commission\'s 6th Framework Program (LSHM-CT-2007-037286). We acknowledge support by the German Research Foundati
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br Conclusion br Acknowledgments These studies were supporte
2018-11-15

Conclusion Acknowledgments These studies were supported by NIH grant, AR019098, and a grant from the Bill and Melinda Gates Foundation. Introduction Topical corticosteroid (TCS) use is one of the most efficient therapeutic anti-inflammatory modalities in dermatology. However, cessation of
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br Signals of barrier homeostasis It
2018-11-15

Signals of barrier homeostasis It still is only partially understood how perturbations of the outer skin surface signal the underlying nucleated layers to initiate the metabolic responses that restore permeability barrier homeostasis. To date, several extracellular signaling mechanisms have been
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br Materials and methods The locoregional
2018-11-15

Materials and methods The locoregional characteristics of ulcerations were also monitored. Eczematous changes (venous or stasis dermatitis) with scaling, redness, pruritus, and occasionally crusting were invariably presented. Lipodermatosclerosis was a common finding and presents a progressive fi
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