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The data correlations from Multiflash and DIPPR were
2019-07-02
The data correlations from Multiflash™ [43] and DIPPR [44] were used for the liquid volume and heat of vaporization. For vapour pressure the curves were regressed from the experimental data present on both the DIPPR [44] and TRC [45] databases. As for liquid heat capacities both the latter databases
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Acknowledgments The authors thank Dr Vladimir Poltoratsky an
2019-07-02
Acknowledgments The authors thank Dr. Vladimir Poltoratsky and Zhihui Xiao for their help with the in vitro FRET assay. Support for this research was provided by Saint John’s University. Introduction We predicted the existence of endothelium-derived contractile factors (EDCFs) in 1982 [1]. In 1
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br The estrogen receptors History and discovery
2019-07-02
The estrogen receptors: History and discovery In 1958, Elwood Jensen discovered the estrogen receptor, the first receptor ever encountered for any hormone, by showing that reproductive female tissues were able to uptake estrogen from the circulation by binding to proteins. He later demonstrated t
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A variety of epidemiological and
2019-07-02
A variety of epidemiological and clinical studies suggest that light alcohol consumption may exert a favorable effects on BP levels but chronic heavy alcohol consumtion causes sustained BP elevation [16], [17]. The hypertensive effect of heavy drinking occurs with all forms of alcohol (i.e. beer win
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UVRAG is a mammalian ortholog of
2019-07-02
UVRAG is a mammalian ortholog of yeast Vps38 and a promoter of autophagy [51,60,61]. It forms distinct complexes with BECN1 (mammalian ortholog of yeast Vps30/Atg6) and the class III phosphatidylinositol 3-kinase (whose catalytic subunit [PIK3C3] is the mammalian ortholog of yeast Vps34) and contrib
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As in our earlier observations the PTPN
2019-07-02
As in our earlier observations, the PTPN22 SNP affected the appearance of β-cell autoimmunity, but in contrast to our earlier report, only a borderline effect of the PTPN22 SNP on the progression to clinical disease was observed in the current analysis [22], [27]. The finding of an effect of the PTP
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E protein was studied using specific anti E antibodies
2019-07-02
E1 protein was studied using specific anti-E1 ARCA EGFP mRNA where in wild type cells and in transfected cells overexpressing the enzyme. The results revealed several unusual characteristics, which are unique to this ubiquitin-activating enzyme. The E1 was translated as a full-length protein and th
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It is not precisely known which of the
2019-07-01
It is not precisely known which of the intramolecular interactions created by the SH2 domain, the SH3–SH2 linker and the SH2–kinase linker are essential for the catalytic activity of Csk or how these interactions regulate Csk activity. Thus far it has been shown that site-directed mutagenesis of SH3
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The predicted mean time to attaining the maximal
2019-07-01
The predicted mean time to attaining the maximal indirect impact is relevant when considering adult vaccination with PCV. Most developed countries do not recommend PCV in adults, believing that with the high coverage in the infant programme, adult disease will (eventually) decline. The US vaccine de
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In addition the TAA treated groups
2019-07-01
In addition, the TAA-treated groups showed a significant reduction in body weight with significantly increased liver weights and sizes compared to control rats, but NJ cotreatment reversed those defects (Table 1). The reduction in body weights could be attributed to the toxic effect of TAA throughou
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br Conclusion br Conflict of interest br
2019-07-01
Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electri
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The occurrence of RNRVAS first reported as an isolated case
2019-07-01
The occurrence of RNRVAS, first reported as an isolated case in 1985 [16], have since been confirmed in dual-chamber pacemaker recipients undergoing 24-h ambulatory electrocardiograms, who report symptoms similar to those of patients suffering from pacemaker syndrome [17,18]. Incidence of RNRVAS
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Limited data exist concerning the long term incidence and
2019-07-01
Limited data exist concerning the long-term incidence and prognosis of Akt Inhibitor IV structure failure after myocardial infarction, particularly in the era of coronary revascularization. New-onset heart failure significantly increases the mortality risk among these patients [23]. Current ICD tri
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br Material and methods br Results A total
2019-07-01
Material and methods Results A total of 4014 subjects were enrolled and registered during the initial recruitment nmda receptor from September 2013 through March 2015. In total, 167 subjects were excluded because of missing pivotal data such as height, body weight, or age (date of birth). Fin
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br Discussion This study shows that the
2019-07-01
Discussion This study shows that the risk of all-cause mortality in patients with atrial fibrillation is directly associated with RDW in a dose-response manner. This association was independent of known risk factors of mortality. Notably, RDW is associated with all-cause mortality regardless of a
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