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SYN-117 Nevertheless other subtype D genes in CRF
2018-11-13
Nevertheless, other subtype D genes in CRF19_cpx (gag and nef) not investigated in this study might also be associated with increased viral replication and in vivo pathogenesis. In HIV-1, Gag and Nef have been documented to contain the highest CD8 epitope density and are more frequently recognized b
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X chromosome plays an important role in the development of
2018-11-13
X chromosome plays an important role in the development of psychiatric disorders (Goldstein et al., 2013; Perrin et al., 2010; Crow, 2013; Ross et al., 2001, 2006). Over-dosage of X-linked escapee genes due to an extra X chromosome was suggested to contribute to the development of psychiatric sympto
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In this issue of Kandioler et al analyzed TP mutations
2018-11-13
In this issue of , Kandioler et al. analyzed TP53 mutations which produce a partial functionality of the protein (decreasing its transcriptional activity to less than 75%) in stage III colon cancer patients (). Relevant of this study is that the authors confined their analyses only to stage III pati
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There is growing evidence of
2018-11-13
There is growing evidence of an accumulation of mutations and mechanisms of resistance to targeted therapies in cancer. Non-small-cell lung cancer (NSCLC) is still an untreatable disease and is the leading cause of cancer related deaths worldwide (). Various strategies have been proposed to increase
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Further points of distinction between the colitis
2018-11-13
Further points of distinction between the colitis of IBD and PSC (data on AISC is lacking) are the differences in the prevalence of pouchitis after restorative ileo-anal (rectal) pouch anastomosis after colectomy, being 2–3 times higher in PSC than UC (Pavlides et al., 2014) and quite comparable if
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Utilizing a recently developed ultrasensitive assay for vita
2018-11-13
Utilizing a recently developed ultrasensitive assay for vitamin C in RBCs and physiologic transport conditions (Li et al., 2012), we propose an original multicomponent hypothesis linking vitamin C to diabetes. The parts of the hypothesis investigated here are whether low ascorbate concentrations occ
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This economic reality possibly prompted
2018-11-12
This economic reality possibly prompted Bairoch (1993:30) to describe the United States as the “mother country and bastion of modern protectionism”. According to Bairoch (1993), although protectionism in the United States dates back to 1860s, the continent recorded the highest global tariff volume i
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br Patients and methods The
2018-11-12
Patients and methods The da Vinci Surgical System was installed in our hospital in September 2006. A total of eight cases of robotic RC were performed for advanced norepinephrine bitartrate cancer by a single surgeon at the Chang Gung Memorial Hospital-Linko between September 2006 and November 20
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Cost effective analysis also showed favorable results With r
2018-11-12
Cost-effective analysis also showed favorable results. With regard to long-term outcomes, no published studies have demonstrated significant differences in freedom from reoperation, differences in degree of postoperative mitral regurgitation, or differences in long-term survival between sternotomy a
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C reactive protein is an acute phase protein
2018-11-12
C-reactive protein is an acute-phase protein produced by hepatocytes on stimulation by IL-6, which indicates a strong correlation between CRP and IL-6. IL-6 production is stimulated by IL-1b. Both IL-1b and IL-6 stimulate the production of IL-1-α, an anti-inflammatory cytokine that antagonizes IL-1
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br Soybeans types of soy
2018-11-12
Soybeans, types of soy food products and their nutritional functions and consumption Soybean isoflavones: genistein, daidzein, glycitein, and formononetin The association of soy isoflavone food consumption with incidence and prognosis of breast cancer Possible molecular mechanisms of chem
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c-myc inhibitor Vitamin A is toxic in high amounts But
2018-11-12
Vitamin A is toxic in high amounts. But, the provitamins such as carotene are not toxic. It is reported that doses such as 40,000–50,000 and 25,000 IUs are toxic for adults and children respectively [2]. So, it is recommended to use β-carotene for fortification of dairy products. Health risks begin
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To explain this effect of GAG mimetics on bone regeneration
2018-11-12
To explain this effect of GAG mimetics on bone regeneration, we hypothesize that it is partly due to their capacity to modulate endogenous MSC properties in vivo. Therefore, to validate this secretin receptor we investigated in this study whether some particular mimetics are able to potentiate effe
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AG-14361 Several pancreatic cancer cell lines and human tiss
2018-11-12
Several pancreatic cancer cell lines and human tissue samples were surveyed for cell surface, intracellular, and functional markers. CD20, CD24, CD44, CD133, CD184 (CXCR4), CD326 (EpCam), Sox-2, and OCT3/4 were examined in established pancreatic cancer cell lines. The functional marker, i.e., SP, wa
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Although H AZK me could be
2018-11-12
Although H2AZK7me1 could be detected by ChIP at the transcriptional start site of a few differentiation markers (Fgf5, FoxA2, and Hand2) in E14 mES cells and the level of methylation decreased from those genes in response to retinoic acid-induced differentiation, we still do not know what H2AZK7me1
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