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During development extrinsic signals in a progenitor s
2018-11-14
During development, extrinsic signals in a progenitor’s microenvironment provide cues for self-renewal and lineage commitment. Although several growth factors, including fibroblast growth factors (FGFs) 2 (Perantoni et al., 1995), 8 (Perantoni et al., 2005), 9, and 20 (Barak et al., 2012) and epider
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gsk-3 Table shows the results of the multivariable linear
2018-11-14
Table 2 shows the results of the multivariable linear regression. Briefly, in crude analyses (adjusting only for urinary creatinine) individuals in the 3rd and 4th quartiles of urinary MEHP had statistically significantly longer LTL compared to the lowest referent quartile (Table 2, Model 1) with ev
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Seventy one individuals aged with CAL
2018-11-14
Seventy one individuals aged C p.(Trp777Arg); c.3610C>G p.(Arg1204GIy); c.4016T>G (p.Leu1339Arg); c.4267A>G p.(Lys1423Glu); c.5425C>T p.(Arg1809Cys); c.6950T>C p.(Leu2317Pro); and also an in frame cytotoxicity assay not present in the parents lymphocyte DNAs (c.3327_3329del p.(Leu1109del)). All of t
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Currently the mechanism by which limb IPC induces upregulati
2018-11-14
Currently, the mechanism by which limb IPC induces upregulation of renal renalase is incomplete clear. Given that remote IPC-activated humoral signaling pathways is involved in the remote organ protection (Gassanov et al., 2014), the circulating cytokines released from the preconditioned limb muscl
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Norway Funding by the Norwegian
2018-11-14
Norway: Funding by the Norwegian Cancer Society and the Norwegian Research Council. The Resource for Lung Cancer in North Trent (ReSoLUCENT)/Sheffield: This study has been supported by Sheffield ECMC (Experimental Cancer Medicine Centre) and Weston Park Hospital Cancer Charity. Tampa, FL: This stu
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To assess if these biomarkers could
2018-11-14
To assess if these biomarkers could predict subsequent diagnosis of lung cancer, we performed association study between the variables and lung cancer. In multivariable logistic regression analyses among all participants from both training and validation sets, the serum levels for the 4 biomarkers we
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It is important to note that Marco does
2018-11-14
It is important to note that Marco does not account for all of the monocyte inflammation caused by RSV infection. Targeted deletion of Marco significantly increased susceptibility to some RSV-induced phenotypes but did not account for all of the genetic variation identified by the strain screen. The
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The authors addressed this question using a meta analytic
2018-11-14
The authors addressed this question using a meta-analytic approach involving 15 studies that examined more than 12,000 smokers (). The study found that there were no differences in the benefits of quitting based on CHRNA5 allelic status. Consistent with many previous studies the benefits of quitting
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The cross talk among adipose tissue
2018-11-14
The cross-talk among adipose tissue, insulin resistance, systemic Blebbistatin and intestinal microbiota is of crucial importance for illustrating the underlying mechanisms of obesity-related diseases. Previous studies have indicated that HFD-induced low-grade inflammation, obesity and diabetes can
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To address these barriers interventions are needed
2018-11-14
To address these barriers, interventions are needed that impact macro-level structural factors, such as reducing poverty and income inequality, increasing educational attainment, and fostering more equitable gender norms. As seen by the Tucker et al. review, social determinants of health matter, and
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br Experimental design materials and methods The
2018-11-14
Experimental design, materials and methods The vineyard is located approximately 15.5km east to the nearest Bureau of Meteorology (BOM) weather station (Ararat Prison Station, Vic, Australian BOM Station No. 089085). The long-term mean January temperature (MJT) and annual average rainfall recorde
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Fig presents the EBSD micrographs obtained for the nanometri
2018-11-14
Fig. 3 presents the EBSD micrographs obtained for the nanometric powders. Analyzing these data revealed the lack of any preferential orientation. Relative densities were measured at 95.8% for the direct-SPS sample (a), and 93.9 for the CIP-SPS sample (b), with a relative density of the green sample
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The first category Building Characteristics describes the pr
2018-11-14
The first category, Building Characteristics, describes the project in physical and technical terms. We chose five variables that intrinsically represent the physical characteristics of an apartment block. The Volume (Vol) of the building in m3, including all interior volumes above ground plus 60% o
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a01 Initial developmental surveys using magnetic resonance i
2018-11-14
Initial developmental surveys using magnetic resonance imaging (MRI) documented morphological a01 differences from childhood to adulthood in several brain regions. For example, frontocortical gray matter volume follows an inverted-U pattern, peaking around age 12, while temporal lobe gray matter vo
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The neural correlates of PE are typically investigated using
2018-11-14
The neural correlates of PE are typically investigated using paradigms in which participants learn how arbitrary stimuli predict positive or negative outcomes. Such paradigms are well suited for examining general aspects of PE learning but may be less well suited for studying socially anxious adoles
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