• Myeloid sarcoma can be observed as a de

  2019-04-22

  

  Myeloid sarcoma can be observed as a de novo malignancy (without leukemic presentation in peripheral blood and bone marrow), during the course of acute myeloid leukemia (AML), affecting 2.5–9% of all AML patients, myelodysplastic syndromes (MDS) or myeloproliferative neoplasms (MPNs, both chronic my

• Acute kidney injury is a common disorder worldwide

  2019-04-22

  

  Acute kidney injury is a common disorder worldwide, occurring in more than 13 million people every year, 85% of whom live in low-income or middle-income countries (LMICs). The disease imposes a severe burden of morbidity and mortality, with a major economic effect on health-care expenditure worldwid

• Conflicts of interest br Acknowledgments

  2019-04-22

  

  Conflicts of interest Acknowledgments This article was supported by grants from the Ministry of Science and Technology, Executive Yuan (MOST 103-2314-B-010-043-MY3), and Taipei Veterans General Hospital (V103C-112; V104C-095; and V105C-096). We also appreciate the Clinical Research Core Laborato

• De manera puntual ambos gobiernos

  2019-04-20

  

  De manera puntual, ambos gobiernos dejaron sentadas sus posiciones ante el nuevo proceso bilateral para normalizar sus relaciones. En su alocución del 17 de diciembre de 2014, el general Raúl Castro destacó, entre otras cosas, que desde su elección como presidente de los consejos de Estado y de Mini

• In focal coronary spastic angina intravascular ultrasound wa

  2019-04-20

  

  In focal coronary spastic angina, intravascular ultrasound was reported to detect intima–media complex thickening and an increased sonolucent zone [16,17], and OCT can detect intimal thickening with low lipid and calcium deposits [18], which are believed to reflect neointimal hyperplasia subsequent

• atr inhibitor br Other drugs Overdose of

  2019-04-20

  

  Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium atr inhibitor and thus to unmask a BrS phenotype [60].

• Although the CHADS score is

  2019-04-20

  

  Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so

• pdgf receptor El recorrido inicia con una

  2019-04-20

  

  El recorrido inicia con una revisión de las colaboraciones de Paz en la revista entre la que destaca la del número 197, de marzo de 1951. El famoso de David Rousset en torno pdgf receptor los campos de concentración en la . Lo que marcaría la ruptura de Paz con la izquierda stalinista latinoameric

• The conventional cutoff for small for gestational age is bas

  2019-04-20

  

  The conventional cutoff for small for gestational age is based on birthweight, which is suitable for infants born at term but is far less appropriate for those born preterm. Preterm birth is itself pathological, and ultrasound-based estimates of fetal weight show that infants born preterm are much s

• In addition we are continuing our regular editorial

  2019-04-20

  

  In addition, we are continuing our regular editorial policies of commissioning more specialised Clinical Reviews and Series across Group to provide a more focused and in-depth assessment for key diseases. And beyond providing knowledge and information, we want to encourage academic and practising c

• En este sentido la idea de crisis alude ante todo

  2019-04-20

  

  En este sentido, la idea de crisis alude ante todo, GDC-0941 una noción de cambio, que puede ser abrupto y radical —como en la noción de cambio revolucionario, o en la teoría de la crisis del capitalismo como colapso; o puede referirse más bien a una modificación o trastocamiento paulatino, crónico

• We report a case of

  2019-04-19

  

  We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con

• br Conclusion br Introduction Multiple

  2019-04-19

  

  Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not

• br Discussion In this pilot

  2019-04-19

  

  Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre

• It is good to see

  2019-04-19

  

  It is good to see any cluster-randomised abacavir trial of a handwashing intervention, much more a successful one. Globally there is considerable funding invested in handwashing promotion, yet the kind of rigorous study published in this month\'s issue of by Adam Biran and colleagues is rare in the

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