• Severe ECG abnormality associated with systolic dysfunction

  2019-05-05

  

  Severe ECG abnormality associated with systolic dysfunction of our DM1 patients. Some degree of electro-mechanical correlation has been demonstrated in several previous studies on DM1 subjects. DM1 patients with prolonged PR or QRS intervals are at four-times higher risk to develop LV systolic dysfu

• The nutrition support team NST estimated his nutritional

  2019-05-05

  

  The nutrition support team (NST) estimated his nutritional status and began the intervention. An inadequate calorie intake (due to swallowing difficulty) induced malnutrition in the patient; his bodyweight (BW) loss exceeded 8% in 3 months, his body mass index (BMI) was 21 kg/m2, triceps skinfold th

• br Methods The prevalence of various fractionation schedules

  2019-05-05

  

  Methods The prevalence of various fractionation schedules was extracted from each of the final articles included in the review. Other relevant information, such as significant predictive factors for the use of single fraction Stattic therapy, changes in the prevalence of fractionation schedules

• More than million almost children younger than years

  2019-05-05

  

  More than 200 million—almost 40%—children younger than 5 years in developing countries are not fulfilling their developmental potential. In parts of Africa, up to three-quarters of children are victims of physical abuse, and a third of girls and more than 10% of boys are victims of sexual abuse. One

• br Methods This prospective study was

  2019-05-04

  

  Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor

• br Interpretation of identified genetic variants and genetic

  2019-05-04

  

  Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected

• Mechanistic target of rapamycin mTOR

  2019-05-04

  

  Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and

• La cam se mantiene hasta nuestros d as en

  2019-05-04

  

  La cam se mantiene hasta nuestros días en resistencia y se ha caracterizado como una organización radicalizada en el rescate de su cultura en, y desde, sus territorios, insiste en ello como condición para la reconstrucción de sus formas religiosas, lengua, autoridades, etc., ya que la autonomía que

• In conclusion a rare KCNE D N polymorphism may modify

  2019-05-04

  

  In conclusion, a rare KCNE1-D85N polymorphism may modify the LQTS phenotype in combination with other pathogenic LQTS-related gene mutations. Disclosures Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is observed in 10–30% of patients with symptomatic K03861

• This population based study demonstrates that

  2019-04-30

  

  This population-based study demonstrates that interventions must change attitudes regarding violence in the home and society, promote positive parenting practices, and tackle the inequality that allows the normalisation of violence and patriarchal power over women and children. Violence does not occ

• En ese contexto Mart nez Estrada que se

  2019-04-30

  

  En ese contexto, Martínez Estrada, que se encontraba en México, fue encargado de recordar gingerol don Alfonso Reyes en representación de Argentina, y de pronunciar las palabras en reconocimiento a los 19 años de Cuadernos, junto con el poeta español Francisco Giner y el filósofo mexicano Luis Villo

• br Discussion Valproic acid is a potent inhibitor of histone

  2019-04-30

  

  Discussion Valproic scopolamine hydrobromide is a potent inhibitor of histone deacetylases (HDAC). It can modify the structure of chromatin allowing recruitment of transcription factors to restore epigenetically suppressed genes. Valproic acid has been shown to possess antiproliferative activity

• tlr signaling br Discussion There is an important

  2019-04-30

  

  Discussion There is an important need for new treatment options for AML in elderly patients. Their frailty imposes limitations upon the aggressiveness of the treatment which can be administered [6,24]. In addition, the poor prognostic disease features often seen in this tlr signaling mean that r

• Cardiac troponin I cTnI is a

  2019-04-30

  

  Cardiac troponin I (cTnI) is a well-established, sensitive, and specific marker of myocardial injury. However, evidence indicates that unrecognized myocardial injury may be occurring with certain conditions such as sepsis without acute coronary ischemic event, which demonstrate elevated cTnI levels.

• In silico prediction software SIFT PolyPhen CADD and other p

  2019-04-30

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

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