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br Authors contributions br Acknowledgements br
2019-08-28
Authors’ contributions Acknowledgements Introduction Retinoic Oligomycin A clinical is a key signalling molecule in healthy development and in differentiation of stem cells, albeit uncontrolled levels of retinoic acid can lead to mutagenesis [1]. In eukaryotes retinoic acid is made by oxida
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br Introduction Benzanthrone BNZ is a
2019-08-28
Introduction Benzanthrone (BNZ) is a dye intermediate used in the synthesis of number of polycyclic vat and disperse dyes. It has been detected as an environmental pollutant in urban ambient air particulates, originating from furnace effluents, municipal refuge, wood and coal combustion and autom
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Recent studies investigating the effects of mesenchymal
2019-08-28
Recent studies investigating the effects of mesenchymal stem cell (MSC) therapy in rodent models including chronic renal failure and glomerulonephritis have demonstrated that MSC therapy can result in beneficial effects [57], [58]. In cats, autologous intra-renal injections of either adipose tissue-
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br Methodology The following subsections describe the
2019-08-28
Methodology The following subsections describe the steps of the Systematic Literature Review (SLR) process we followed [9]. Results In our review of the literature, we used the definitions provided by the IEEE Standard Computer Dictionary [15] to categorize the claims about the effectiveness
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br Conflict of interest statement
2019-08-27
Conflict of interest statement References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements We acknowledge financial support by the Swiss State Secretariat for Education, Research and Innovation (Federal
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Interest in DGKs increased as it became clear
2019-08-27
Interest in DGKs increased as it became clear that not only are they important for lipid homeostasis, they serve to modulate the relative levels of diacylglycerol (DAG) and phosphatidic azd1775 (PtdOH) that play critical roles in a variety of signaling pathways (Eichmann and Lass, 2015; Liu et al.,
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TNF-alpha, recombinant human protein br Acknowledgments This
2019-08-27
Acknowledgments This work was supported by Natural Science Foundation of China (No: 81501485). We are particularly grateful to Dr. Dan Yang and Dr. Yi Zhang for their assistance and facilities in helping this experiment and manuscript. Oral squamous cell carcinoma (OSCC), the most common malig
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Finally our results suggest that R may at least partially
2019-08-27
Finally, our results suggest that σ2R may, at least partially, mediate the hunger-suppressive action of amphetamine by interacting with orexigenic receptors in CRF2R-OX1R heteromer contexts. Despite extensive evidence supporting the formation of GPCR oligomers in heterologous systems, the lack of ap
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A more refined picture of cholinesterase activity patterns
2019-08-27
A more refined picture of cholinesterase activity patterns may be obtained by measuring ChE activity of the same sample before and after addition of certain cholinesterase inhibitors, with differential specificity for different components of total ChE activity, such as BW284c51 (BW1,5-bis-(4-allyldi
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We then analyzed Ki proliferation
2019-08-27
We then analyzed Ki-67 proliferation index as a categorical variable by using 15%, essentially the median Ki-67 value in the entire study group (see above), to delineate low and high proliferation subgroups. By Fisher\'s exact test, both the type 1 versus non-type 1 EWS-FLI1 comparison (P = 0.047; T
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The structure of the HOIP RBR LDD
2019-08-27
The structure of the HOIP RBR–LDD module bound to UbcH5~Ub reveals insights into an activated HOIP component [47]. Contacts between the E2~Ub and the non-cognate RBR module in the crystal suggest how a structure in which the active sites of the E2 and the E3 are in close proximity might look. In thi
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First of all two assumptions just as in
2019-08-26
First of all, two assumptions just as in Ref. [30] are need to simplify the penetration process: (1) The crater phases is short and the berbamine of EFP is consumed little; thus, the influence of crater on penetration can be ignored; (2) the initial stagnation radial pressure is equal to axial pres
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Abbas et al studied the mitigation of ASR in
2019-08-26
Abbas et al. studied the mitigation of ASR in their corresponding study by incorporating RHA [1]. These researchers used Ordinary Portland Cement (OPC), four different percentages (i.e., 10%, 20%, 30% and 40% by weight of OPC) of RHA and reactive aggregate (sand from Dolomite-limestone rock) in thei
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Within the X CX PX RX motif
2019-08-26
Within the X1CX3PX5RX7 motif of several prokaryotic FGE substrates, the residues of X3, X5, and X7 are variably found as mixtures of alanine, glycine, threonine, or serine residues [26], [27]. The docked model of our identified HCTPRRP motif revealed that position X1 (H1) and position X7 (P7) were n
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While we previously demonstrated that TraG
2019-08-26
While we previously demonstrated that TraG is inhibited by specific transglycosylase inhibitors and that enzymatic activity is strongly reduced upon mutation of the potential catalytic core (Arends et al., 2013), the enzymatic mechanism of both domains was not assigned. Here, by mass spectrometry an
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