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The first part of the study evaluated the
2020-01-21
The first part of the study evaluated the accuracy of recomLine IgG and IgG Avidity to date CMV infection: In our study, 83.1% of samples tested matched onset dates compared to 71.9% with VIDAS avidity. Moreover, the number of inconclusive results (intermediate avidity for VIDAS, positive IgG withou
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It is also meaningful to discuss whether VSOR
2020-01-21
It is also meaningful to discuss whether VSOR Cl− channel-induced apoptosis is correlated with the ER pathway. Thus, in this study, we sought to clarify the intrinsic relationship between VSOR Cl− channels and the level of ER stress-related proteins. The research results are as follows: the expressi
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Additionally although the membrane localized
2020-01-21
Additionally, although the membrane-localized ER signaling described in this review has generally been studied in isolation from nuclear signaling, it is becoming clearer and clearer that integration of these mechanisms must be considered (Frick, 2015). Perhaps the distinct estradiol signaling mecha
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The current study had the following aims br Materials
2020-01-20
The current study had the following 3 aims: Materials and methods Results Discussion Western Europe, USA/Canada, and Australia have traditionally been the areas in which cochlear AP26113 australia is most common [9], [10]; correspondingly, the most common and well-known validated tests and
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Sampling sediments is usually performed with grab corers
2020-01-20
Sampling sediments is usually performed with grab corers [16], [29]. The digested sludge analyzed by Ternes et al. [16] was taken directly from the digester and the activated sludge was obtained by AR-12 of the slurry of STPs [16]. Collected samples are transported under cooled conditions (+4 or −2
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As for the molecular mechanism Ferguson BD
2020-01-20
As for the molecular mechanism, Ferguson BD suggested that EphB4/EphrinB2 stimulation induced topoisomerase I activity in small cell lung cancer cell lines. Treatment of ccr5 antagonist with EphrinB2/Fc induced topoisomerase activity as assessed by DNA relaxation in cells with high EphB4 expression
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To elucidate whether the impact of hypoxia
2020-01-20
To elucidate whether the impact of hypoxia on EGFR expression is cell context specific or culturing density dependent, we chose the following cancer MK-4827 mg driven by EGFR and evaluated the EGFR expression after hypoxia treatment at different culturing density: a highly aggressive and poorly dif
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Given a disruption of membrane internalization and an increa
2020-01-20
Given a disruption of membrane internalization and an increase in synaptic glutamate receptors in CPG2 knockdown neurons, one might expect an increase in dendritic spine size as membrane continues to be inserted into the spines during receptor exocytosis. However, we observed the opposite phenotype,
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The CPA parameters of SO were calculated
2020-01-20
The CPA parameters of SO2 were calculated based on Eq. (11) using the vapor pressure and saturated liquid density data of SO2 over the reduced temperature range of 0.55 to 0.9. All of the data used were taken from the NIST database [53]. The resulting CPA parameters of SO2 are presented in Table S1
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In our opinion the precise function of AE of S
2020-01-20
In our opinion, the precise function of AE of S. mansoni (Sm32) remains unclear, and accurate knowledge of the three dimensional structure of this enzyme would be valuable for a better understanding the molecular basis of many of its properties, including its role in the host-parasite interaction, a
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Bcl Family Set I To provide a brief critical evaluation of t
2020-01-19
To provide a brief critical evaluation of this technology and an outlook, we note that performance of SMEPT is critically dependent on each of the components making up this platform, namely the substrate, the enzyme, and the prodrug. With regards to the latter, SMEPT is built on the experience and s
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Abdominal aortic aneurysm AAA is considered a
2020-01-19
Abdominal aortic aneurysm (AAA) is considered a major health concern and is associated with extremely high rates of mortality in case of aortic rupture. The main pathophysiologic mechanisms leading to aortic dilation include the degradation of the extracellular matrix (ECM) components, such as colla
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It has previously been established that
2020-01-19
It has previously been established that DDRs play an important role in collagen regulation in at least two distinct ways: (1) activation of DDRs by collagen results in up-regulation of the matrix metalloproteinases, which results in cleavage and degradation of the ECM20., 21., [22] and (2) Terifluno
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However there are still some issues that remain poorly under
2020-01-19
However, there are still some issues that remain poorly understood. For instance, how TGF-β modulates DDR2 expression and whether Smads participate in the regulation. How does DDR2 regulate the expression of PTHrP via Runx2? Is there any other kinase downstream of DDR2 participating in PTHrP regulat
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UCF 101 Another novel finding of our study was
2020-01-19
Another novel finding of our study was that the global 5 hmC was down-regulated and was associated with a substantial reduction of TET expression in the PE placentas compared with the controls. The decreased global 5 hmC level was consistent with the increased global 5 mC level in the preeclamptic p
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