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Overall we found maternal antibiotics to be associated
2024-04-10
Overall, we found maternal Chlorpropamide to be associated with improved outcomes. In these multiple logistic regression models, high postnatal empiric infant antibiotic exposure was not significantly associated with risk for NEC or LOS. However, consistent with previous studies,5, 6 receipt of high
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br Method of literature search br Disclosures
2024-04-10
Method of literature search Disclosures Acknowledgment The authors thank and acknowledge Mrs. Jaini Parekh, BFA, for illustrating the diagram in Figure 1. An overview of angiogenesis Angiogenesis is a biological process through which there is the formation of new blood vessels from pre-
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br Acknowledgments br Introduction Alzheimer s disease AD is
2024-04-10
Acknowledgments Introduction Alzheimer's disease (AD) is a severe neurodegenerative disorder primarily affecting the elderly population. Senile plaques in the brain, one of the pathological hallmarks of AD, are formed by the accumulation of aggregated β-amyloid (Aβ) with an extensive β-sheet s
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br Conclusion br Conflict of interest br Introduction Oral
2024-04-09
Conclusion Conflict of interest Introduction Oral cancer may originate from lips, lower and upper alveolar ridges, hard palate, sublingual region, buccal mucosa, anterior two-thirds of the tongue as well as retromolar trigone and floor of the mouth (World Health Organization, 2013). As the
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In eukaryotes class III ACs including
2024-04-09
In eukaryotes, class III ACs (including GCs) are almost universally present, with the noteworthy exception of higher plants. Our dataset comprises 9690 sequences of class III nucleotide cyclases from 710 eukaryotic species. Approximately 80% thereof belong to subclass IIIa and 10% to subclasses IIIb
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Bedaquiline mg Although the effects of adenosine receptor
2024-04-09
Although the effects of adenosine receptor signaling in acute renal IRI have been attributed to the generation of high concentrations of adenosine, we have recently reported an increase in kidney levels of both AMP and adenosine, with a concomitant fall in ATP and ADP. We have also previously demons
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ADOR immunoreactivity was high in parasympathetically innerv
2024-04-09
ADOR immunoreactivity was high in parasympathetically-innervated smooth muscle, namely the iris sphincter muscle and the ciliary muscle. No ADOR immunoreactivity was noted in the sympathetically-innervated iris dilator muscle. Immunoreactivity against all four ADORs was noted in the ciliary epitheli
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AdipoRon is an orally active
2024-04-09
AdipoRon is an orally active, synthetic small molecule that activates adiponectin receptor (AdipoR). It mimics the antidiabetic effects of adiponectin, exhibiting its effect through the activation of AMPK and PPARα pathways via AdipoR1 and AdipoR2, respectively (Fig. 2) [62]. AdipoR activation has r
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The purpose of this study is to
2024-04-09
The purpose of this 172 5 synthesis study is to examine the relationship between ACEs and engagement in treatment among a sample of youth in residential treatment centers (RTCs). It is hypothesized that youth with higher ACE scores will have lower levels of engagement in treatment. In order to thor
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br Experimental procedure br Introduction Migraine
2024-04-09
Experimental procedure Introduction Migraine is a debilitating neurovascular disorder characterized by recurring unilateral pulsating headaches of moderate to severe intensity, associated with nausea, photophobia and/or phonophobia, lasting from 4 to 72 h (Headache Classification Committee of
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Acknowledgments br P c is expressed
2024-04-09
Acknowledgments P450c17 is expressed in several steroidogenic tissues, including the adrenal cortex, the ovary, and the testes (). Thus, 17α-hydroxylase/17,20-lyase is a key enzyme required for the production of both cortisol and sex steroids. This enzyme defect blocks the synthesis of cortisol,
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For the NSCLC patients with EGFR activating mutations
2024-04-09
For the NSCLC patients with EGFR-activating mutations, EGFR-TKIs (gefitinib and erlotinib) are effective clinical therapies [21], [22]. However, approximately 10% of patients harboring EGFR-sensitizing mutations exhibit intrinsic resistance, and up to 40% do not attain a major response to treatment
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br Autophagy and cell death pathways in ischemic stroke Alth
2024-04-09
Autophagy and cell death pathways in ischemic stroke Although very important for the effects on post-ischemic Argatroban sale injury, autophagy is not the only mechanism of action involved in cell death. Necrosis and apoptosis are two other distinct forms of cell death with great difference in mo
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NOXA a BH only protein is
2024-04-09
NOXA, a BH3-only protein, is best known as a selective inhibitor of MCL-1, which is a highly expressed pro-survival protein in many human malignancies [30]. In addition, NOXA was recently proven to act as a direct activator via directly binding to BAX to induce apoptosis [31]. Given that its levels
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exemplifies three of the compounds investigated in the
2024-04-09
exemplifies three of the compounds investigated in the selection for a candidate drug (CD). Our first criteria was an IC The Metaphit as such did not show any genotoxicity in the SOS/umu assay, but this does not say anything about any possible genotoxicity of its metabolites or degradation products.
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