Introduction Glioblastoma multiforme GBM is

2018-10-20

Introduction Glioblastoma multiforme (GBM) is the most common adult primary TG101348 tumor, with an extremely dismal prognosis and high rate of recurrence following standard therapy (Wen and Kesari, 2008). Populations of brain tumor initiating cells (BTICs), which express many of the properties of

Although the FDA considers analogous cell product data

2018-10-20

Although the FDA considers analogous cell product data an acceptable option for preclinical studies, it requires substantial similarity between analogous animal and human products (FDA, 2013). Due to the significant differences in the innate and adaptive immune system (Mestas and Hughes, 2004), hema

The mouse intestinal epithelium is

2018-10-20

The mouse intestinal epithelium is renewed through intestinal stem cells (ISCs) every 3–4 days (Barker, 2014). The “stem cell zone” model identifying crypt PHA-793887 columnar (CBC) cells at the base of the intestinal crypt (Cheng and Leblond, 1974) and “+4 stem cell” model identifying a ring of ce

Hello world!

2018-07-29